A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors
Abstract Introduction: Natural Killer (NK) cells play a key role in both innate and adaptive immune responses against viruses and…
prognostic value
Comprehensive pan-cancer analysis of PPP1R3G reveals its diagnostic, prognostic, and immunotherapeutic implications
Abstract Background: PPP1R3G, a regulatory subunit of protein phosphatase 1, plays a critical role in glycogen metabolism and has been…
Systematic pan-cancer analyses of the potential function of the Golgi scaffold protein PAQR3
Abstract Progesterone and AdipoQ Receptor 3 (PAQR3) is a member of the AdipoQ receptor. Our previous studies have found that…
Exploring the immunological role and prognostic potential of PPM1M in pan-cancer
Abstract Methods: Samples of cancer and normal tissues were obtained from the cancer genome atlas and genotype-tissue expression. Kaplan–Meier survival…
Prognostic value and immunological role of Kruppel-like transcription factor 9 gene in pan-carcinoma
Abstract Methods: A series of bioinformatics methods were used to analyze the relationship between KLF9 and tumor prognosis, tumor mutation…
Oncogenetic Function and Prognostic Value of DNA Topoisomerase II Alpha in Human Malignances: A Pan-Cancer Analysis
Abstract Increasing studies have revealed significant associations between TOP2A with oncogenesis and prognosis of human cancers; however, pan-cancer analysis has…
Multi-Omics Analysis of MCM2 as a Promising Biomarker in Pan-Cancer
Abstract Minichromosome maintenance 2 (MCM2) is a member of the minichromosomal maintenance family of proteins that mainly regulates DNA replication…
Prognostic and Immunotherapeutic Roles of KRAS in Pan-Cancer
Abstract KRAS is one well-established tumor-driver gene associated with cancer initiation, development, and progression. Nonetheless, comparative studies of the relevance…
CD155-Prognostic and Immunotherapeutic Implications Based on Multiple Analyses of Databases Across 33 Human Cancers
Abstract Growing evidence has suggested that CD155 participates in the regulation of many biological processes ranging cell growth, invasion, and…