KRAS is a prognostic biomarker associated with diagnosis and treatment in multiple cancers
Abstract KRAS encodes K-Ras proteins, which take part in the MAPK pathway. The expression level of KRAS is high in…
prognostic biomarker
Multi‐omics analysis of the oncogenic value of copper Metabolism‐Related protein COMMD2 in human cancers
Abstract Background: The copper metabolism MURR1 domain (COMMD) protein family is involved in tumorigenicity of malignant tumors. However, as the…
DHRS7 is an immune-related prognostic biomarker of KIRC and pan-cancer
Abstract Renal clear cell carcinoma (KIRC) is one malignancy whose development and prognosis have been associated with aberrant DHRS7 expression.…
Integrative study reveals the prognostic and immunotherapeutic value of CD274 and PDCD1LG2 in pan-cancer
Abstract Background: Disorders of CD274 and PDCD1LG2 contribute to immune escape in human cancers, and treatment with anti-programmed death receptor…
REV1: A novel biomarker and potential therapeutic target for various cancers
Abstract Background: REV1 is a member of the translesion synthesis DNA polymerase Y family. It is an essential player in…
FDX1 expression predicts favourable prognosis in clear cell renal cell carcinoma identified by bioinformatics and tissue microarray analysis
Abstract Ferredoxin 1 (FDX1), an iron-sulphur protein, is responsible for electron transfer in a range of metabolic redox reactions. Clear…
Pan-cancer analysis of CREB3L1 as biomarker in the prediction of prognosis and immunotherapeutic efficacy
Abstract Background: CAMP response element binding protein 3-like 1 (CREB3L1) has been indicated as a critical biomarker and can modulate…
AP3S1 is a Novel Prognostic Biomarker and Correlated With an Immunosuppressive Tumor Microenvironment in Pan-Cancer
Abstract Background: Adaptor-related protein complex 3, sigma one subunit (AP3S1) is one of the encoding subunits of the adaptor complex…
POC1A, prognostic biomarker of immunosuppressive microenvironment in cancer
Abstract POC1 centriolar protein A (POC1A) effect in pan-cancer remains uncertain. The POC1A expression in normal and tumor tissues underwent…
Identifying the critical states and dynamic network biomarkers of cancers based on network entropy
Abstract Background: There are sudden deterioration phenomena during the progression of many complex diseases, including most cancers; that is, the…