Abstract Background: The enzyme 2′-5′-oligoadenylate synthetase 3 (OAS3) plays a well-established role in antiviral immunity, but its involvement in cancer…
Abstract Objectives: The aim of this study is to investigate the role of epithelial cell transforming sequence 2 (ECT2) as…
Abstract Background: Glyoxalase 1 (GLO1), an enzyme responsible for breaking down methylglyoxal (MG), is increasingly recognized as a tumor-promoting factor…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1186/s40001-025-03404-7. Article type: Research Article Keywords: LMBR1L expression, Tumor…
Abstract Background: The 7‐Dehydrocholesterol reductase (DHCR7), a critical enzyme catalyzing the final step of the cholesterol biosynthesis pathway, has gained…
Abstract Background: EME1, a critical DNA repair endonuclease, has emerged as a potential oncogene implicated in genome instability and cancer…
Abstract Background: Cell division cycle 6 (CDC6) is a key licensing factor for DNA replication in the G1 and S…
Abstract Proteasome subunit beta type-9 (PSMB9), a member of the proteasome beta subunit family, encodes the pivotal β1i component of…
Abstract Background and aim: Protein kinase D1 (PRKD1), a serine/threonine kinase, regulates cellular processes such as proliferation, apoptosis, migration, and…
Abstract RIN3, a member of the RIN protein family, plays a pivotal role in disease progression by modulating Rab5 activity…