Integrative analysis of the potential of DISP3 as a biomarker for thyroid cancer
Abstract Background: Thyroid cancer (THCA) is a common endocrine malignancy with diverse prognostic outcomes. The role of dispatched RND transporter…
prognosis
LMO2 confers value as a potential immunotherapy marker in pan-cancer analysis and inhibits progression of Clear Cell Renal Cell Carcinoma
Abstract Full pan-cancer analysis of LMO2 with immunotherapeutic target assessment. ZC3h13 mediated m6A modification controls LMO2 expression in ccRCC. LMO2…
Comprehensive bioinformatics analysis unveils THEMIS2 as a carcinogenic indicator related to immune infiltration and prognosis of thyroid cancer
Abstract The aim of this study was to identify biomarkers associated with the initiation and prognosis of thyroid cancer and…
Comprehensive analysis of BTNL9 as a prognostic biomarker correlated with immune infiltrations in thyroid cancer
Abstract Background: Thyroid cancer (THCA) is the most common type of endocrine cancers, and the disease recurrences were usually associated…
GEMIN4, a potential therapeutic targets for patients with basal-like subtype breast cancer
Abstract Background: Basal-like breast cancer (BLBC) takes up about 10–20% of all breast cancer(BC), what’s more, BLBC has the lowest…
A pan-cancer analysis of the prognostic value of long non-coding RNA LINC00662 in human cancers
Abstract Background: Numerous studies have revealed that the long non-coding RNA LINC00662 is irregularly expressed in various cancers, as well…
Integrative analysis deciphers the heterogeneity of cancer-associated fibroblast and implications on clinical outcomes in ovarian cancers
Keywords: scRNA-seq, Single-cell RNA-sequencing, CAFs, Cancer-associated fibroblasts, HGSOC, High-grade serous ovarian carcinoma, TCGA, The Cancer Genomics Atlas, LUAD, Lung adenocarcinoma,…
HOXA-AS2 may be a potential prognostic biomarker in human cancers: A meta-analysis and bioinformatics analysis
Abstract Background: Dysregulation of long non-coding (lncRNA) has been reported in various solid tumors. HOXA cluster antisense RNA 2 (HOXA-AS2)…
Prognostic value of TIGIT in East Asian patients with solid cancers: A systematic review, meta-analysis and pancancer analysis
Abstract Background: T-cell immunoreceptor with Ig and ITIM domains (TIGIT) participates in tumor immune escape by delivering inhibitory signals to…
Pan-cancer analyses identify DCBLD2 as an oncogenic, immunological, and prognostic biomarker
Abstract Discoidin, CUB, and LCCL domain-containing protein 2 (DCBLD2) is a two-domain transmembrane protein-coding gene located on chromosome 3, the…