Abstract Objectives: With the increasing application of high-throughput transcriptomic data in cancer research, identifying reliable cancer biomarkers in high-dimensional settings…
Abstract Novel interventions for post-traumatic stress disorder (PTSD) leverage the psychoactive properties of psychedelic compounds, such as ketamine, 3,4-methylenedioxymethamphetamine and…
Abstract Differentiated thyroid carcinoma (DTC) is the most common endocrine malignancy and typically has a favorable prognosis. However, a subset…
Abstract CYP2C9 and CYP2C19 are major CYP450 enzymes that heavily influence the hepatic metabolism and bioactivation of many medications, including…
Abstract Background/Objectives: Pharmacogenetic (PGx) testing can predict drug efficacy, toxicity, and risk of adverse drug reactions (ADRs). However, PGx-guided prescribing…
Abstract Introduction: Chronic pain affects approximately 30% of the global population, posing a significant public health challenge. Despite their widespread…
Abstract Plain Language Summary: Creatine transporter deficiency (CRTR‐D) is a rare genetic disorder causing mental, behavioral, and movement problems. More…
Abstract Simple Summary: This review summarizes the pivotal role of tumor-infiltrating immune cells (TIICs) within the tumor microenvironment (TME) and…
Abstract Background: The precise characterization of individual tumors and immune microenvironments using transcriptome sequencing has provided a great opportunity for…
Abstract Conventional therapy options for chronic pain are still insufficient and patients most frequently request alternative medical treatments, such as…