The Role of Post-Translational Modifications in Necroptosis
Abstract Necroptosis, a distinct form of regulated necrosis implicated in various human pathologies, is orchestrated through sophisticated signaling pathways. During…
post-translational modifications (PTMs)
Phosphorylation Regulates CIRBP Arginine Methylation, Transportin-1 Binding and Liquid-Liquid Phase Separation
Abstract Arginine-glycine(-glycine) (RG/RGG) regions are highly abundant in RNA-binding proteins and involved in numerous physiological processes. Aberrant liquid-liquid phase separation…
The Cannabis Proteome Draft Map Project
Abstract Recently we have seen a relaxation of the historic restrictions on the use and subsequent research on the Cannabis…
Top-Down Proteomics of Medicinal Cannabis
Abstract The revised legislation on medicinal cannabis has triggered a surge of research studies in this space. Yet, cannabis proteomics…
Histone chaperone exploits intrinsic disorder to switch acetylation specificity
Abstract Histones, the principal protein components of chromatin, contain long disordered sequences, which are extensively post-translationally modified. Although histone chaperones…