Pharmacogenetic association study of cannabis use in chronic pain
Abstract Background: Pain is one of the leading causes of disability worldwide. Despite the various pharmacological treatments available, patients with…
pharmacogenetics
Predicting therapy dropout in chronic pain management: a machine learning approach to cannabis treatment
Abstract Introduction: Chronic pain affects approximately 30% of the global population, posing a significant public health challenge. Despite their widespread…
Supporting Machine Learning Model in the Treatment of Chronic Pain
Abstract Conventional therapy options for chronic pain are still insufficient and patients most frequently request alternative medical treatments, such as…
Association between ABCB1 rs2235048 Polymorphism and THC Pharmacokinetics and Subjective Effects following Smoked Cannabis in Young Adults
Abstract Genetic influences on acute responses to psychoactive drugs may contribute to individual variability in addiction risk. ABCB1 is a…
In Silico Pharmacogenetics CYP2D6 Study Focused on the Pharmacovigilance of Herbal Antidepressants
Abstract The annual increase in depression worldwide together with an upward trend in the use of alternative medicine as treatment…
Anti-emetic drugs in oncology: pharmacology and individualization by pharmacogenetics
Abstract Objective Nausea and vomiting are the most distressful side effects of cytotoxic drugs in cancer patients. Antiemetics are commonly…