Peroxisomes, PPARs, and Their Role in Macrophages
Abstract Macrophages are versatile immune cells capable of modifying their functions based on their location and the specific requirements of…
peroxisomes
Peroxisome Dysfunction and Steatotic Liver Disease
Abstract Peroxisomes are cellular organelles involved in multiple metabolic processes, including lipid oxidation, lipid synthesis, and the metabolism of reactive…
Peroxisomal Alterations in Prostate Cancer: Metabolic Shifts and Clinical Relevance
Abstract Peroxisomes have attracted growing interest for their potential role in prostate cancer, a disease characterized by metabolic features distinct…
Modelling Peroxisomal Disorders in Zebrafish
Abstract Peroxisomes are ubiquitous, dynamic, oxidative organelles with key functions in cellular lipid metabolism and redox homeostasis. They have been…
Regulation of Mitochondrial and Peroxisomal Metabolism in Female Obesity and Type 2 Diabetes
Abstract Obesity and type 2 diabetes (T2D) are widespread metabolic disorders that significantly impact global health today, affecting approximately 17%…
NUDT7 regulates total hepatic CoA levels and the composition of the intestinal bile acid pool in male mice fed a Western diet
Abstract Nudix hydrolase 7 (NUDT7) is an enzyme that hydrolyzes CoA species, is highly expressed in the liver, and resides…
Insights Into the Peroxisomal Protein Inventory of Zebrafish
Abstract Peroxisomes are ubiquitous, oxidative subcellular organelles with important functions in cellular lipid metabolism and redox homeostasis. Loss of peroxisomal…
Peroxisomal Metabolite and Cofactor Transport in Humans
Abstract Peroxisomes are membrane-bound organelles involved in many metabolic pathways and essential for human health. They harbor a large number…
Organelle interplay—peroxisome interactions in health and disease
Abstract Peroxisomes are multifunctional, dynamic, membrane‐bound organelles with important functions in cellular lipid metabolism, rendering them essential for human health…
Functional characterisation of peroxisomal β-oxidation disorders in fibroblasts using lipidomics
Abstract Electronic supplementary material: The online version of this article (doi:10.1007/s10545-017-0076-9) contains supplementary material, which is available to authorized users.…