Peroxisomes, PPARs, and Their Role in Macrophages
Abstract Macrophages are versatile immune cells capable of modifying their functions based on their location and the specific requirements of…
peroxisome proliferator-activated receptors (PPARs)
Interaction Between Peroxisome Proliferator-Activated Receptors and Cannabidiol in the Gut of Chickens Applied to Different Challenge Conditions
Abstract Peroxisome proliferator-activated receptors (PPARs) are important targets for cannabidiol (CBD), which mediate many of its biological actions. The hypothesis…
Regulation of Mitochondrial and Peroxisomal Metabolism in Female Obesity and Type 2 Diabetes
Abstract Obesity and type 2 diabetes (T2D) are widespread metabolic disorders that significantly impact global health today, affecting approximately 17%…
Maternal Cannabis Use during Lactation and Potential Effects on Human Milk Composition and Production: A Narrative Review
Abstract Cannabis use has increased sharply in the last 20 y among adults, including reproductive-aged women. Its recent widespread legalization…
Role of Phytoconstituents as PPAR Agonists: Implications for Neurodegenerative Disorders
Abstract Peroxisome proliferator-activated receptors (PPAR-γ, PPAR-α, and PPAR-β/δ) are ligand-dependent nuclear receptors that play a critical role in the regulation…
The Endocannabinoid System and PPARs: Focus on Their Signalling Crosstalk, Action and Transcriptional Regulation
Abstract Peroxisome proliferator-activated receptors (PPARs) are a family of nuclear receptors including PPARα, PPARγ, and PPARβ/δ, acting as transcription factors…
Relevance of Peroxisome Proliferator Activated Receptors in Multitarget Paradigm Associated with the Endocannabinoid System
Abstract Cannabinoids have shown to exert their therapeutic actions through a variety of targets. These include not only the canonical…
CannabinEYEds: The Endocannabinoid System as a Regulator of the Ocular Surface Nociception, Inflammatory Response, Neovascularization and Wound Healing
Abstract The endocannabinoid system (ECS) is a complex regulatory system, highly conserved among vertebrates. It has been widely described in…