Plant essential oil targets TRPV3 for skin renewal and structural mechanism of action
Abstract Our skin safeguards the body homeostasis for health and also provides psychological consolation in social life. Natural essential oils…
Patch clamp
In vitro inhibition of voltage-dependent sodium currents by the antifungal drug amorolfine
Abstract Voltage-gated sodium (Nav) channels are critical for electrical signaling, and their pharmacological modulation can be leveraged for the development…
Analgesic effect of a mixed T-type channel inhibitor/CB2 receptor agonist
Abstract Background: Cannabinoid receptors and T-type calcium channels are potential targets for treating pain. Here we report on the design,…