Estrogen-related genes for thyroid cancer prognosis, immune infiltration, staging, and drug sensitivity
Abstract Background: Thyroid cancer (THCA) has become increasingly common in recent decades, and women are three to four times more…
papillary thyroid cancer
Establishment and validation of a novel risk model based on CD8T cell marker genes to predict prognosis in thyroid cancer by integrated analysis of single-cell and bulk RNA-sequencing
Abstract Papillary thyroid cancer (PTC) is a histological type of thyroid cancer, and CD8T is important for the immune response.…
TTK is a potential regulator of tumor progression correlated with dedifferentiation and immune cell infiltration in papillary thyroid cancer
Abstract Objective: To investigate the role and clinical significance of threonine tyrosine kinase (TTK) in papillary thyroid cancer (PTC). Methods:…
Comprehensive analysis of BTNL9 as a prognostic biomarker correlated with immune infiltrations in thyroid cancer
Abstract Background: Thyroid cancer (THCA) is the most common type of endocrine cancers, and the disease recurrences were usually associated…
A biomarker and molecular mechanism investigation for thyroid cancer
Abstract Introduction: This study aimed to reveal the potential molecular mechanism associated with thyroid cancer (THCA) prognosis, and investigate promising…
Integrated analysis of tumor microenvironment features to establish a diagnostic model for papillary thyroid cancer using bulk and single-cell RNA sequencing technology
Abstract Background: Characterizing tumor microenvironment using single-cell RNA sequencing has been a promising strategy for cancer diagnosis and treatment. However,…
The novel oncogenic factor TET3 combines with AHR to promote thyroid cancer lymphangiogenesis via the HIF-1α/VEGF signaling pathway
Abstract Background: Lymphangiogenesis has been reported to play crucial roles in the metastasis of thyroid cancer (THCA), but despite the…
Bioinformatics analysis of the prognostic and clinical value of senescence-related gene signature in papillary thyroid cancer
Abstract Cellular senescence can both inhibit and promote the occurrence of tumors, so how to apply cellular senescence therapy is…
Identification of m6A-associated LncRNAs as predict factors for the immune infiltration and prognosis of thyroid cancer
Abstract Objective: This study aims to evaluate the prognostic value of m6A-associated long noncoding RNAs (lncRNAs) and their interaction with…
The role of lactate metabolism-related LncRNAs in the prognosis, mutation, and tumor microenvironment of papillary thyroid cancer
Abstract Background: Lactate, a byproduct of glucose metabolism, is primarily utilized for gluconeogenesis and numerous cellular and organismal life processes.…