Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s10238-025-01882-x. Article type: Research Article Keywords: ACSL3, Pan-cancer analysis,…
Abstract Background: MRPL3, a member of the mitochondrial ribosomal family, is involved in the translation of mitochondria-related proteins. However, its…
Abstract Background: Acetyl-CoA carboxylase alpha (ACACA), a crucial rate-limiting enzyme governing de novo biosynthesis of fatty acids, drives oncogenic metabolic…
Abstract Background: EME1, a critical DNA repair endonuclease, has emerged as a potential oncogene implicated in genome instability and cancer…
Abstract Objective: Homer scaffold protein 1 (HOMER1), a postsynaptic scaffold protein, regulates excitatory synapses and intracellular signaling and has been…
Abstract Introduction: TEA domain transcription factor 4 (TEAD4), a key effector of the Hippo signaling pathway, has been increasingly associated…
Abstract Background: 4-aminobutyric acid aminotransferase (ABAT) is a pivotal enzyme for mitochondrial metabolism and central nervous system homeostasis, with known…
Abstract Background: Cell division cycle 6 (CDC6) is a key licensing factor for DNA replication in the G1 and S…
Abstract Background: Immunoglobulin superfamily member 8 (IGSF8) is a membrane protein implicated in crucial biological processes like cell interactions and…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-15082-w. Article type: Research Article Keywords: TRPM4, Sodium-induced cell…