METTL7B is a novel prognostic biomarker of lower-grade glioma based on pan-cancer analysis
Abstract Methyltransferase-like 7B (METTL7B) is a member of the methyltransferase-like protein family that plays an important role in the development…
Pan-cancer analysis
Pairwise correlation of genes involved in glucose metabolism: a potential diagnostic marker of cancer?
Abstract Cancer is a highly malignant disease, killing approximately 10 million people worldwide in 2020. Cancer patient survival substantially relies…
Prognostic and immunological role of CD36: A pan-cancer analysis
Abstract CD36 plays a critical role in lipid metabolism, which is closely associated with human immunity. However, the role of…
Pan-Cancer Prognostic, Immunity, Stemness, and Anticancer Drug Sensitivity Characterization of N6-Methyladenosine RNA Modification Regulators in Human Cancers
Abstract N6-methyladenosine RNA modification plays a significant role in the progression of multiple tumorigenesis. Our study identified the imperative role…
Clinical and prognostic pan-cancer analysis of m6A RNA methylation regulators in four types of endocrine system tumors
Abstract N6-methyladenosine (m6A), internal modification of mRNA, has recently been reported to be an important regulatory mechanism affecting tumor proliferation.…
Systematic Analysis of Coronavirus Disease 2019 (COVID-19) Receptor ACE2 in Malignant Tumors: Pan-Cancer Analysis
Abstract Background: Coronavirus disease 2019 (COVID-19) was first detected in patients with pneumonia in December 2019 in China and it…
Integrative omics analysis reveals relationships of genes with synthetic lethal interactions through a pan-cancer analysis
Keywords: ACC, adrenocortical carcinoma, BLCA, bladder urothelial carcinoma, BRCA, breast invasive carcinoma, CESC, cervical squamous cell carcinoma and endocervical adenocarcinoma,…
Pan-Cancer Analysis Reveals the Diverse Landscape of Novel Sense and Antisense Fusion Transcripts
Abstract Gene fusions that contribute to oncogenicity can be explored for identifying cancer biomarkers and potential drug targets. To investigate…
A pan-cancer analysis of driver gene mutations, DNA methylation and gene expressions reveals that chromatin remodeling is a major mechanism inducing global changes in cancer epigenomes
Abstract Background: Recent large-scale cancer sequencing studies have discovered many novel cancer driver genes (CDGs) in human cancers. Some studies…
Pan-cancer analysis of long non-coding RNA NEAT1 in various cancers
Abstract Changes in the abundance and activity of long non-coding RNAs (lncRNAs) have an important impact on the development of…