Unlocking the Antidiabetic Potential of CBD: In Vivo Preclinical Studies
Abstract Background/Objectives: Diabetes mellitus is a growing global health concern, driving the exploration of new therapies like cannabidiol (CBD), which…
OGTT
O-GlcNAcylation: an important post-translational modification and a potential therapeutic target for cancer therapy
Abstract O-linked β-d-N-acetylglucosamine (O-GlcNAc) is an important post-translational modification of serine or threonine residues on thousands of proteins in the…
NASH-related increases in plasma bile acid levels depend on insulin resistance
Abstract Background & Aims: Plasma bile acids (BAs) have been extensively studied as pathophysiological actors in non-alcoholic steatohepatitis (NASH). However,…
Epigenetic activation of O-linked β-N-acetylglucosamine transferase overrides the differentiation blockage in acute leukemia
Abstract Background: Overriding the differentiation blockage in acute myeloid leukemia (AML) is the most successful mode-of-action in leukemia therapy –…