Abstract All-trans retinoic acid (ATRA) is an established differentiation therapy for acute promyelocytic leukemia (APL), but its effect in other…
Abstract Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by motor and non-motor symptoms, including cognitive decline, which plays…
Abstract Methylmalonic acidemia (MMAemia) is an inborn error of organic acid metabolism characterized by the accumulation of toxic metabolites—including methylmalonic…
Abstract Autism spectrum disorder (ASD) is a common neurodevelopmental condition mainly characterized by both a scarce aptitude for social interactions…
Abstract Preserving the function and survival of pancreatic beta-cells, in order to achieve long-term glycemic control and prevent complications, is…
Abstract Studying the complex molecular mechanisms involved in traumatic brain injury (TBI) is crucial for developing new therapies for TBI.…
Abstract In late December 2019, a novel coronavirus (SARS-CoV-2 or CoV-19) appeared in Wuhan, China, causing a global pandemic. SARS-CoV-2…
Abstract Cancer cachexia (CC) is a multifactorial syndrome characterized by systemic inflammation, uncontrolled weight loss and dramatic metabolic alterations. This…
Abstract Glioblastoma (GBM) is the most malignant brain tumor and one of the deadliest types of solid cancer overall. Despite…