Synthetic cannabinoids use in a sample of opioid-use disorder patients
Abstract Cannabis is the most widely consumed illegal drug in the world and synthetic cannabinoids are increasingly gaining popularity and…
novel synthetic cannabinoids (NSCs)
In Vivo Bio-Activation of JWH-175 to JWH-018: Pharmacodynamic and Pharmacokinetic Studies in Mice
Abstract 3-(1-Naphthalenylmethyl)-1-pentyl-1H-indole (JWH-175) is a synthetic cannabinoid illegally marketed for its psychoactive cannabis-like effects. This study aimed to investigate and…
Detection of the Synthetic Cannabinoids AB-CHMINACA, ADB-CHMINACA, MDMB-CHMICA, and 5F-MDMB-PINACA in Biological Matrices: A Systematic Review
Abstract Simple Summary: Synthetic cannabinoids were originally developed for scientific research and potential therapeutic agents. However, clandestine laboratories synthesize them…
Clinical pattern of synthetic cannabinoids users in Upper Egypt: cross-sectional study
Abstract Background: There is an expanding use of new psychoactive substances containing synthetic cannabinoids in the last years. This study…
Adulteration of low‐delta‐9‐tetrahydrocannabinol products with synthetic cannabinoids: Results from drug checking services
Abstract Since late 2019, low‐delta‐9‐tetrahydrocannabinol (THC) preparations adulterated with synthetic cannabinoids (SCs) have been frequently observed in Switzerland. The unawareness…
Major Phytocannabinoids and Their Related Compounds: Should We Only Search for Drugs That Act on Cannabinoid Receptors?
Abstract The most important discoveries in pharmacology, such as certain classes of analgesics or chemotherapeutics, started from natural extracts which…
Pharmacological and Toxicological Effects of Phytocannabinoids and Recreational Synthetic Cannabinoids: Increasing Risk of Public Health
Abstract Synthetic Cannabinoids (CBs) are a novel class of psychoactive substances that have rapidly evolved around the world with the…
Clinical withdrawal symptom profile of synthetic cannabinoid receptor agonists and comparison of effects with high potency cannabis
Abstract Synthetic cannabinoid receptor agonists (SCRAs) may be used as an alternative to natural cannabis; however, they may carry a…
The Endocannabinoid System and Cannabidiol: Past, Present, and Prospective for Cardiovascular Diseases
Abstract In the past, cannabis was commonly associated with mysticism and illegality. Fortunately, in recent years perspectives and discourses have…
Pharmacological Properties, Therapeutic Potential and Molecular Mechanisms of JWH133, a CB2 Receptor-Selective Agonist
Abstract The endocannabinoid system has attracted attention as a pharmacological target for several pathological conditions. Cannabinoid (CB2)-selective agonists have been…