In vivo assessment of the nephrotoxic effects of the synthetic cannabinoid AB-FUBINACA
Abstract Background: The widespread misuse of synthetic cannabinoids (SCs) has led to a notable increase in reported adverse effects, raising…
novel synthetic cannabinoids (NSCs)
JWH-182: a safe and effective synthetic cannabinoid for chemotherapy-induced neuropathic pain in preclinical models
Abstract Chemotherapy-induced neuropathic pain (CINP), a condition with unmet treatment needs, affects over half of cancer patients treated with chemotherapeutics.…
An Internet Snapshot Survey Assessing the sale of Synthetic Cannabinoid Receptor Agonists for use with Electronic Vaping Devices
Abstract Introduction: Synthetic cannabinoid receptor agonists (SCRAs) are associated with significant toxicity and are increasingly used in electronic vaping devices.…
Perioperative Cannabinoids Significantly Reduce Postoperative Opioid Requirements in Patients Undergoing Coronary Artery Bypass Graft Surgery
Abstract Background Opioids, commonly used to control pain associated with surgery, are known to prolong the duration of mechanical ventilation…
Differential cannabinoid‐like effects and pharmacokinetics of ADB‐BICA, ADB‐BINACA, ADB‐4en‐PINACA and MDMB‐4en‐PINACA in mice: A comparative study
Abstract Despite synthetic cannabinoids’ (SCs) prevalent use among humans, these substances often lack comprehensive pharmacological data, primarily due to their…
The synthetic cannabinoid 5-fluoro ABICA upregulates angiogenic markers and stimulates tube formation in human brain microvascular endothelial cells
Abstract Objective: Synthetic cannabinoids (SCs), a class of psychoactive compounds emulating the effects of natural cannabis, have prompted addiction and…
The synthetic cannabinoids menace: a review of health risks and toxicity
Abstract Graphical Abstract: Article type: Review Article Keywords: Synthetic cannabinoids, Spices, Designer drugs, Toxicity Authors: Ayman Alzu’bi ⚬, Fatimah Almahasneh,…
Cardiac effects of 5F-Cumyl-PEGACLONE
Abstract Synthetic cannabinoids become increasingly popular as a supposedly safe and legal alternative to cannabis. In order to circumvent the…
Aberrant salience in cannabis-induced psychosis: a comparative study
Abstract Background: Natural Cannabis (NC) and Synthetic Cannabinoids (SCs) use can increase the risk and exacerbate the course of psychotic…
Subtle Structural Modification of a Synthetic Cannabinoid Receptor Agonist Drastically Increases its Efficacy at the CB1 Receptor
Abstract The emergence of synthetic cannabinoid receptor agonists (SCRAs) as illicit psychoactive substances has posed considerable public health risks, including…