Receptor Binding Affinities of Synthetic Cannabinoids Determined by Non-Isotopic Receptor Binding Assay
Abstract A major predictor of the efficacy of natural or synthetic cannabinoids is their binding affinity to the cannabinoid type…
novel synthetic cannabinoids (NSCs)
Lateral flow immunoassay and enzyme linked immunosorbent assay as effective immunomethods for the detection of synthetic cannabinoid JWH-200 based on the newly synthesized hapten
Keywords: BSA, bovine serum albumin, DCC, DIBAH, diisobutylaluminium hydride, DMF, ELISA, enzyme-linked immunosorbent assay, GAR, goat anti-rabbit antibody, GAR-Po, peroxidase…
Novel Psychoactive Substances—Recent Progress on Neuropharmacological Mechanisms of Action for Selected Drugs
Abstract A feature of human culture is that we can learn to consume chemical compounds, derived from natural plants or…
Psychostimulant Effect of the Synthetic Cannabinoid JWH-018 and AKB48: Behavioral, Neurochemical, and Dopamine Transporter Scan Imaging Studies in Mice
Abstract JWH-018 and AKB48 are two synthetic cannabinoids (SCBs) belonging to different structural classes and illegally marketed as incense, herbal…
Distribution of Synthetic Cannabinoids JWH-210, RCS-4 and ∆ 9-Tetrahydrocannabinol After Intravenous Administration to Pigs
Abstract Background: Synthetic cannabinoids (SCs) have become an increasing issue in forensic toxicology. Controlled human studies evaluating pharmacokinetic data of…
Motor vehicle collisions caused by the ‘super-strength’ synthetic cannabinoids, MAM-2201, 5F-PB-22, 5F-AB-PINACA, 5F-AMB and 5F-ADB in Japan experienced from 2012 to 2014
Abstract From 2012 to 2014 in Japan, 214 cases of motor vehicle collisions were attributed to the use of illegal…
Vaping Synthetic Cannabinoids: A Novel Preclinical Model of E-Cigarette Use in Mice
Abstract Smoking is the most common route of administration for cannabis; however, vaping cannabis extracts and synthetic cannabinoids (“fake marijuana”)…
Assessing the experience of using synthetic cannabinoids by means of interpretative phenomenological analysis
Abstract Background: New psychoactive substances (NPS) have been increasingly consumed by people who use drugs in recent years, which pose…
Genotoxic properties of XLR-11, a widely consumed synthetic cannabinoid, and of the benzoyl indole RCS-4
Abstract Aim of this study was the investigation of the genotoxic properties of XLR-11 [1-(5-fluoropentyl)-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)methanone, a widely consumed synthetic cannabinoid…
Assessment of the Abuse Liability of Synthetic Cannabinoid Agonists JWH-030, JWH-175, and JWH-176
Abstract The emergence and use of synthetic cannabinoids have greatly increased in recent years. These substances are easily dispensed over…