Abstract Protein oligomerization is key to countless physiological processes, but also to abnormal amyloid conformations implicated in over 25 mortal…
Abstract Heme oxygenase (HO) converts heme to carbon monoxide, biliverdin, and free iron, products that are essential in cellular redox…
Abstract Saccharomyces cerevisiae TBP associated factor 14 (Taf14) is a well-studied transcriptional regulator that controls diverse physiological processes and that…
Abstract Regulated proteolysis by proteasomes involves ~800 enzymes for substrate modification with ubiquitin, including ~600 E3 ligases. We report here…
Abstract Cannabis sativa L. is one of the most-studied species for its phytochemistry due to the abundance of secondary metabolites,…
Abstract Myosin VI plays crucial roles in diverse cellular processes. In autophagy, Myosin VI can facilitate the maturation of autophagosomes…
Abstract ITCH (aka Atrophin-1-interacting protein 4) is a prominent member of the NEDD4 HECT (Homologous to E6AP C-Terminus) E3 ubiquitin…
Abstract Conformation and dynamics of a chaperone-client interaction at the atomic level show a basic underlying mechanism. Article type: Research…
Abstract Bone Morphogenetic Proteins (BMPs) are secreted protein hormones that act as morphogens and exert essential roles during embryonic development…
Abstract Characterisation of the structure and dynamics of large biomolecules and biomolecular complexes by NMR spectroscopy is hampered by increasing…