Changes in the Bacterial Communities of Biocomposites with Different Flame Retardants
Abstract In today’s world, the use of environmentally friendly materials is strongly encouraged. These materials derive from primary raw materials…
Next Generation Sequencing (NGS)
Pan-cancer repository of validated natural and cryptic mRNA splicing mutations
Abstract We present a major public resource of mRNA splicing mutations validated according to multiple lines of evidence of abnormal…
Substantial batch effects in TCGA exome sequences undermine pan-cancer analysis of germline variants
Abstract Background: In recent years, research on cancer predisposition germline variants has emerged as a prominent field. The identity of…
Combining DNA methylation and RNA sequencing data of cancer for supervised knowledge extraction
Abstract Background: In the Next Generation Sequencing (NGS) era a large amount of biological data is being sequenced, analyzed, and…
Treatment of Periodontal Ligament Stem Cells with MOR and CBD Promotes Cell Survival and Neuronal Differentiation via the PI3K/Akt/mTOR Pathway
Abstract Periodontal ligament mesenchymal stem cells (hPDLSCs), as well as all mesenchymal stem cells, show self-renewal, clonogenicity, and multi-tissue differentiation…
Diversity and evolution of the repetitive genomic content in Cannabis sativa
Abstract Background: The repetitive content of the genome, once considered to be “junk DNA”, is in fact an essential component…
Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions
Abstract Nuclear RNA metabolism is influenced by protein complexes connecting to both RNA-productive and -destructive pathways. The ZC3H18 protein binds…
Cannabidiol Modulates the Immunophenotype and Inhibits the Activation of the Inflammasome in Human Gingival Mesenchymal Stem Cells
Abstract Human Gingival Mesenchymal Stem Cells (hGMSCs) are multipotential cells that can expand and differentiate in culture under specific and…
Cannabis microbiome sequencing reveals several mycotoxic fungi native to dispensary grade Cannabis flowers
Abstract The Center for Disease Control estimates 128,000 people in the U.S. are hospitalized annually due to food borne illnesses.…
MRI characterisation of adult onset alpha-methylacyl-coA racemase deficiency diagnosed by exome sequencing
Abstract Background: Correct diagnosis is pivotal to understand and treat neurological disease. Herein, we report the diagnostic work-up utilizing exome…