The epiMelanoma test enables plasma-based detection of melanoma and prediction of immunotherapy response
Abstract Background: Melanoma is one of the most serious skin cancers worldwide, often progressing without obvious symptoms. Early detection is…
Next-generation sequencing
Pan-cancer analysis to character the clinicopathological and genomic features of KRAS-mutated patients in China
Abstract Purpose: The Kirsten rat sarcoma viral oncogene (KRAS) is the most frequently mutated oncogene in human cancers. Significant advancements…
Next-generation sequencing identified that RET variation associates with lymph node metastasis and the immune microenvironment in thyroid papillary carcinoma
Abstract Background: To date, although most thyroid carcinoma (THCA) achieves an excellent prognosis, some patients experience a rapid progression episode,…
A Novel Truncating Mutation in HOMER2 Causes Nonsyndromic Progressive DFNA68 Hearing Loss in a Spanish Family
Abstract Nonsyndromic hereditary hearing loss is a common sensory defect in humans that is clinically and genetically highly heterogeneous. So…
A reference library for Canadian invertebrates with 1.5 million barcodes, voucher specimens, and DNA samples
Abstract The reliable taxonomic identification of organisms through DNA sequence data requires a well parameterized library of curated reference sequences.…
Impact of Nitrogen Nutrition on Cannabis sativa: An Update on the Current Knowledge and Future Prospects
Abstract Nitrogen (N) availability represents one of the most critical factors affecting cultivated crops. N is indeed a crucial macronutrient…
Generation of a Comprehensive Transcriptome Atlas and Transcriptome Dynamics in Medicinal Cannabis
Abstract Cannabinoids are the main medicinal compounds of interest in the plant Cannabis sativa, that are primarily synthesised in the…
Pan-cancer analysis of intratumor heterogeneity associated with patient prognosis using multidimensional measures
Abstract Human cancers accumulate various mutations during development and consist of highly heterogeneous cell populations. This phenomenon is called intratumor…