The Potential of Hair Matrix for Biomarker Analysis in Schizophrenia
Abstract Schizophrenia (SCZ) is a complex psychiatric disorder with positive, negative, and cognitive symptoms that cause long-term functional impairment. Despite…
neurotransmitters
Neuropharmacology of Neuropathic Pain: A Systematic Review
Abstract Neuropathic pain, a debilitating condition, remains challenging to manage effectively. An insight into neuropharmacological mechanisms is critical for optimizing…
Basal forebrain-lateral habenula inputs and control of impulsive behavior
Abstract Deficits in impulse control are observed in several neurocognitive disorders, including attention deficit hyperactivity (ADHD), substance use disorders (SUDs),…
Synaptic changes in psychiatric and neurological disorders: state-of-the art of in vivo imaging
Abstract Synapses are implicated in many neuropsychiatric illnesses. Here, we provide an overview of in vivo techniques to index synaptic…
Control of a hippocampal recurrent excitatory circuit by cannabinoid receptor-interacting protein Gap43
Abstract The type-1 cannabinoid receptor (CB1R) is widely expressed in excitatory and inhibitory nerve terminals, and by suppressing neurotransmitter release,…
Synaptic Plasticity Abnormalities in Fetal Alcohol Spectrum Disorders
Abstract The brain’s ability to strengthen or weaken synaptic connections is often termed synaptic plasticity. It has been shown to…
Early-Stage High-Concentration Thiacloprid Exposure Induced Persistent Behavioral Alterations in Zebrafish
Abstract As a major neonicotinoid insecticide, thiacloprid (THCP) is frequently detected in aquatic environments worldwide due to its heavy use,…
Cell type specific cannabinoid CB1 receptor distribution across the human and non-human primate cortex
Abstract Alterations in cannabinoid CB1 receptor (CB1R) are implicated in various psychiatric disorders. CB1R participates in both depolarization induced suppression…
Exploration of Multiverse Activities of Endocannabinoids in Biological Systems
Abstract Over the last 25 years, the human endocannabinoid system (ECS) has come into the limelight as an imperative neuro-modulatory…
Structural and molecular characterization of paraventricular thalamic glucokinase‐expressing neuronal circuits in the mouse
Abstract The thalamic paraventricular nucleus (PVT) is a structure highly interconnected with several nuclei ranging from forebrain to hypothalamus and…