Just a SNP away: The future of in vivo massively parallel reporter assay
Abstract The human genome is largely noncoding, yet the field is still grasping to understand how noncoding variants impact transcription…
neurodevelopmental and neurodegenerative effects
Neurological Disorders Induced by Drug Use: Effects of Adolescent and Embryonic Drug Exposure on Behavioral Neurodevelopment
Abstract Clinical studies demonstrate that the risk of developing neurological disorders is increased by overconsumption of the commonly used drugs,…
Traditional and Innovative Anti-seizure Medications Targeting Key Physiopathological Mechanisms: Focus on Neurodevelopment and Neurodegeneration
Abstract Despite the wide range of compounds currently available to treat epilepsy, there is still no drug that directly tackles…
Recent Research on Cannabis sativa L.: Phytochemistry, New Matrices, Cultivation Techniques, and Recent Updates on Its Brain-Related Effects (2018–2023)
Abstract Cannabis sativa L. is a plant that humankind has been using for millennia. The basis of its widespread utilization…
Emerging Roles of Endocannabinoids as Key Lipid Mediators for a Successful Pregnancy
Abstract In recent years, Cannabis use/misuse for treating pregnancy-related symptoms and other chronic conditions has increased among pregnant women, favored…
El papel de los cannabinoides en los trastornos del neurodesarrollo de niños y adolescentes
Abstract Introducción.: Los trastornos del neurodesarrollo tienen una etiología multifactorial que resulta de la interacción entre factores biológicos y ambientales.…
The Autism–Psychosis Continuum Conundrum: Exploring the Role of the Endocannabinoid System
Abstract Evidence indicates shared physiopathological mechanisms between autism and psychosis. In this regard, the endocannabinoid system has been suggested to…
Clinical findings from the landmark MEF2C ‐related disorders natural history study
Abstract Introduction: MEF2C‐related disorders are characterized by developmental and cognitive delay, limited language and walking, hypotonia, and seizures. A recent…
Intersection between social inequality and emotion regulation on emerging adult cannabis use
Abstract Emotion regulation challenges place emerging adults (EA) at risk for cannabis use. Emotion dysregulation and social inequality interact during…
Palmitoylethanolamide and Its Biobehavioral Correlates in Autism Spectrum Disorder: A Systematic Review of Human and Animal Evidence
Abstract Autism spectrum disorder (ASD) pathophysiology is not completely understood; however, altered inflammatory response and glutamate signaling have been reported,…