Stress, a Brief Update
Abstract Stress is fundamental for health and adaptation; it is an evolutionarily conserved response that involves several systems in the…
neurobiology
Cannabidiol Impairs Brain Mitochondrial Metabolism and Neuronal Integrity
Abstract Background: The mechanisms underlying the clinical effects of CBD remain poorly understood. Given the increasing evidence for CBD’s effects…
Peripheral biomarkers of treatment-resistant schizophrenia: Genetic, inflammation and stress perspectives
Abstract Treatment-resistant schizophrenia (TRS) often results in severe disability and functional impairment. Currently, the diagnosis of TRS is largely exclusionary…
The Synaptic Interactions of Alcohol and the Endogenous Cannabinoid System
Abstract PURPOSE: A growing body of evidence has implicated the endocannabinoid (eCB) system in the acute, chronic, and withdrawal effects…
Role of Cannabidiol in the Therapeutic Intervention for Substance Use Disorders
Abstract Drug treatments available for the management of substance use disorders (SUD) present multiple limitations in efficacy, lack of approved…
Zur Komorbidität von Posttraumatischer Belastungsstörung und Sucht in biopsychosozialer Perspektive
Abstract Posttraumatische Belastungsstörung und Substanzkonsumstörungen treten im medizinischen Versorgungssystem häufig koexistent auf. Ihre Komorbidität geht mit schwerwiegenderen akuten klinischen Symptombildern,…
The cannabis withdrawal syndrome: current insights
Abstract The cannabis withdrawal syndrome (CWS) is a criterion of cannabis use disorders (CUDs) (Diagnostic and Statistical Manual of Mental…
Review of available studies of the neurobiology and pharmacotherapeutic management of trichotillomania
Keywords: Trichotillomania (TTM), Neurobiology, Rating scales, Clinical trials Authors: Jacklyn Johnson, Abir T. El-Alfy License: © 2015 Production and hosting…
Pathways from Cannabis to Psychosis: A Review of the Evidence
Abstract The nature of the relationship between cannabis use (CU) and psychosis is complex and remains unclear. Researchers and clinicians…