Abstract Epilepsy is one of the most common, severe, chronic, potentially life-shortening neurological disorders, characterized by a persisting predisposition to…
Abstract Ionotropic glutamate receptors (iGluRs) mediate the majority of excitatory neurotransmission and are implicated in various neurological disorders. In this…
Abstract Recently, increasing numbers of studies have demonstrated that transient receptor potential ankyrin 1 (TRPA1) can be used as a…
Abstract Transient receptor potential vanillin 3 (TRPV3) is a member of the transient receptor potential (TRP) superfamily. As a Ca2+-permeable…
Abstract The endocannabinoid and orexin neuromodulatory systems serve key roles in many of the same biological functions such as sleep,…
Abstract The origins of the major classes of current anti-emetics are examined. Serendipity is a recurrent theme in discovery of…