Symptomatic management in multiple sclerosis
Abstract Multiple sclerosis (MS) is the commonest cause of disability in young adults. While there is increasing choice and better…
Multiple sclerosis
Cannabis-induced alterations in brain activation during a test of information processing speed in patients with MS
Abstract Objective: The objective of this article is to determine the functional brain correlates of information processing speed in multiple…
Narrative review of the safety and efficacy of marijuana for the treatment of commonly state-approved medical and psychiatric disorders
Abstract The present investigation aimed to provide an objective narrative review of the existing literature pertaining to the benefits and…
Multiple sclerosis-induced neuropathic pain: pharmacological management and pathophysiological insights from rodent EAE models
Abstract In patients with multiple sclerosis (MS), pain is a frequent and disabling symptom. The prevalence is in the range…
A mechanism-based classification of pain in multiple sclerosis
Abstract Pharmacological treatment of pain in multiple sclerosis (MS) is challenging due to the many underlying pathophysiological mechanisms. Few controlled…
Cannabidiol protects oligodendrocyte progenitor cells from inflammation-induced apoptosis by attenuating endoplasmic reticulum stress
Abstract Cannabidiol (CBD) is the most abundant cannabinoid in Cannabis sativa that has no psychoactive properties. CBD has been approved…
Cannabinoid Modulation of Neuroinflammatory Disorders
Abstract In recent years, a growing interest has been dedicated to the study of the endocannabinoid system. The isolation of…
Cannabidiol in Humans—The Quest for Therapeutic Targets
Abstract Cannabidiol (CBD), a major phytocannabinoid constituent of cannabis, is attracting growing attention in medicine for its anxiolytic, antipsychotic, antiemetic…
New approaches in the management of spasticity in multiple sclerosis patients: role of cannabinoids
Abstract Cannabinoids such as Cannabis-based medicinal extracts (CBMEs) are increasingly being used in the treatment of spasticity associated with multiple…
Cannabinoids in the management of spasticity associated with multiple sclerosis
Abstract The endocannabinoid system and cannabinoid-based treatments have been involved in a wide number of diseases. In particular, several studies…