Eye tracking as a digital biomarker in neurodegenerative diseases
Abstract Oculomotor abnormalities are a common finding in neurodegenerative diseases due to degeneration of neural pathways and brain regions involved…
Multiple sclerosis
Chronic Pain in Multiple Sclerosis: Mechanisms, Clinical Characteristics and Treatment Strategies
Abstract Chronic pain is an underestimated and undertreated yet highly prevalent symptom in people with multiple sclerosis (pwMS), significantly impairing…
ABCB1 polymorphisms are associated with clinical response to nabiximols in patients with multiple sclerosis-related spasticity
Keywords: Multiple sclerosis, Single nucleotide polymorphisms, Nabiximols, Spasticity, ABCB1 Authors: Alessandra Gemma, Marco Mauri, Paola Banfi, Maurizio Versino, Alen Zollo,…
Cannabis and Cognitive Function in Multiple Sclerosis: Findings From a Large Consecutive Clinical Sample
Abstract Background: Cannabis is commonly used in persons with MS (pwMS) for symptom relief. Previous studies investigating the effects of…
Immunomodulatory Role of Mesenchymal Stem Cell Therapy in Multiple Sclerosis: A Systematic Review
Abstract The progressive immune-mediated disease known as multiple sclerosis (MS) is characterized by myelin degradation, inflammation, and neurodegeneration. Recent research…
Evaluating Vaporized Cannabinoid Therapy in Multiple Sclerosis: Findings from a Prospective Single-Center Clinical Study
Abstract Introduction: Multiple Sclerosis (MS) is associated with a wide range of debilitating symptoms, and conventional therapies often fail to…
Neuroprotective and Anti-Inflammatory Effects of Dimethyl Fumarate, Monomethyl Fumarate, and Cannabidiol in Neurons and Microglia
Abstract Dimethyl fumarate (DMF) is an immunomodulatory treatment for multiple sclerosis (MS) that can cross the blood–brain barrier, presenting neuroprotective…
Cannabinoids for spasticity in patients with multiple sclerosis: A systematic review and meta-analysis
Abstract Background: One of the most disabling symptoms of patients with multiple sclerosis (MS) is spasticity which affects their quality…
Disease-Modifying Symptomatic Treatment (DMST) Potential of Cannabinoids in Patients with Multiple Sclerosis
Abstract With the recent introduction of a number of highly effective disease-modifying treatments (DMTs) and the resulting almost complete prevention…
Efficacy of cannabinoids compared to the current standard treatments on symptom relief in persons with multiple sclerosis (CANSEP trial): study protocol for a randomized clinical trial
Abstract Background: Multiple sclerosis (MS) is an inflammatory and degenerative disease of the central nervous system. More than 90,000 Canadians…