Inflammaging and Immunosenescence in the Post‐COVID Era: Small Molecules, Big Challenges
Abstract Aging naturally involves a decline in biological functions, often triggering a disequilibrium of physiological processes. A common outcome is…
monoamine oxidases A and B
The analgesic effects of insulin and its disorders in streptozotocin‐induced short‐term diabetes
Abstract Evidence suggests that insulin resistance plays an important role in developing diabetes complications. The association between insulin resistance and…
Chemical and Biological Evaluation of Novel 1H-Chromeno[3,2-c]pyridine Derivatives as MAO Inhibitors Endowed with Potential Anticancer Activity
Abstract About twenty molecules sharing 1H-chromeno[3,2-c]pyridine as the scaffold and differing in the degree of saturation of the pyridine ring,…
β-Carboline Alkaloids in Soy Sauce and Inhibition of Monoamine Oxidase (MAO)
Abstract Monoamine oxidase (MAO) oxidizes neurotransmitters and xenobiotic amines, including vasopressor and neurotoxic amines such as the MPTP neurotoxin. Its…
Synthetic cannabinoid receptor agonists are monoamine oxidase‐A selective inhibitors
Abstract Synthetic cannabinoid receptor agonists (SCRAs) are one of the fastest growing classes of recreational drugs. Despite their growth in…
Prolonged efavirenz exposure reduces peripheral oxytocin and vasopressin comparable to known drugs of addiction in male Sprague Dawley rats
Abstract Introduction: Several drugs of abuse (DOA) are capable of modulating neurohypophysial hormones, such as oxytocin (OT) and vasopressin (VP),…
Oxidative cyclization of N-methyl-dopa by a fungal flavoenzyme of the amine oxidase family
Abstract Flavin-dependent enzymes catalyze many oxidations, including formation of ring structures in natural products. The gene cluster for biosynthesis of…