Conkazal-M1 from the MKAVA family of conotoxins – a dual-function protease inhibitor and neuroactive peptide
Abstract Marine cone snails produce a diverse array of bioactive peptides, known as conotoxins, in their venom. Given their high…
Molecular evolution
Domesticated cannabinoid synthases amid a wild mosaic cannabis pangenome
Abstract Cannabis sativa is a globally important seed oil, fibre and drug-producing plant species. However, a century of prohibition has…
A bivalent remipede toxin promotes calcium release via ryanodine receptor activation
Abstract Multivalent ligands of ion channels have proven to be both very rare and highly valuable in yielding unique insights…