New psychoactive substances in roadway crash victims in California
Abstract Background: Motor vehicle crashes (MVCs) are a major global health concern. While alcohol continues to be a significant contributor…
mitragynine
Pharmacokinetic Interaction of Kratom and Cannabidiol in Male Rats
Abstract Kratom and cannabidiol products are used to self-treat a variety of conditions, including anxiety and pain, and to elevate…
New Trend in Toxicological Screening Using Volumetric Absorptive Microsampling (VAMS) and High-Resolution Mass Spectrometry (HR/MS) Combination
Abstract In toxicology, screenings are routinely performed using chromatographic methods coupled to detection systems such as high-resolution mass spectrometry (HR/MS).…
Mitragynine (Kratom)-Induced Cognitive Impairments in Mice Resemble Δ9-THC and Morphine Effects: Reversal by Cannabinoid CB1 Receptor Antagonism
Abstract Kratom is a widely abused plant-based drug preparation with a global interest in recent years, well beyond its native…
Antinociceptive Action of Isolated Mitragynine from Mitragyna Speciosa through Activation of Opioid Receptor System
Abstract Cannabinoids and opioids systems share numerous pharmacological properties and antinociception is one of them. Previous findings have shown that…