Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-026-36939-8. Article type: Research Article Keywords: Cannabis smoke extract,…
Abstract Methylmalonic acidemia (MMAemia) is an inborn error of organic acid metabolism characterized by the accumulation of toxic metabolites—including methylmalonic…
Abstract Anaplastic thyroid cancer (ATC) and papillary thyroid carcinoma (PTC) exhibit significant differences in clinical behavior and immune microenvironments, particularly…
Abstract Background: Dedifferentiated thyroid cancer (DDTC) is a highly malignant, infiltrative neoplasm. Studies confirm mitochondrial (MD) dysfunction links to DDTC’s…
Abstract The cannabinoid receptor 1 (CB1R) regulates cardiovascular functions and is activated by agonists such as WIN55,212‐2. While CB1R activation…
Abstract Age-related cognitive decline and neurodegenerative diseases, such as Alzheimer’s disease, represent major global health challenges, particularly with an aging…
Abstract Plant secondary metabolites (PSMs) are a diverse group of bioactive compounds, including flavonoids, polyphenols, saponins, and terpenoids, which have…
Abstract Neurodegenerative diseases constitute a global health issue and a major economic burden. They significantly impair both cognitive and motor…
Abstract The enduring relationship between humanity and the cannabis plant has witnessed significant transformations, particularly with the widespread legalization of…
Abstract The global increase in the aging population has led to a rise in many age-related diseases with continuing unmet…