Cannabidiol as a Prophylactic Agent Against Glioblastoma Growth: A Preclinical Investigation
Abstract Glioblastoma (GBM) remains one of the most lethal brain tumors, with current therapies offering limited benefits and high relapse…
MGMT
MGMT, NUPR1, NDRG2, and GLI1 Gene Promoter Methylation in Glioblastoma Tissues and Association with Clinical Characteristics and Therapeutic Outcomes
Abstract Glioblastoma (GBM) is the most prevalent and devastating form of primary brain tumors in adults, with dismal survival despite…
O-6-Methylguanine-DNA methyltransferase expression is associated with pituitary adenoma tumor recurrence: a systematic meta-analysis
Abstract O-6-methylguanine-DNA methyltransferase (MGMT) reportedly counteracts the cytotoxic effects of the alkylating agent temozolomide. MGMT expression is often low in…