Abstract Glucokinase regulatory protein (GCKR) is a metabolic regulator implicated in glucose homeostasis, but its genetic and functional roles in…
Abstract Background: Glutamine metabolic reprogramming is a hallmark of tumor progression and is highly correlated with poor clinical outcomes. The…
Abstract Background: Little is known on how metabolic reprogramming potentially prompts transition of activated and resting CD4+ memory T cells…
Abstract Simple Summary: Reduced response to glucocorticoids (GCs, such as dexamethasone, Dex), first-line drugs employed during therapy induction, is considered…
Abstract Acid–base homeostasis is a fundamental property of living cells, and its persistent disruption in human cells can lead to…
Abstract Mitochondrial pyruvate carrier 1 (MPC1) is a key metabolic protein that regulates the transport of pyruvate into the mitochondrial…