Abstract Background: Monoacylglycerol lipase (MAGL) is a key serine hydrolase which terminates endocannabinoid signaling and regulates arachidonic acid driven inflammatory…
Abstract Simple Summary: Cannabinoids have been shown to suppress tumour cell proliferation, tumour invasion, metastasis, angiogenesis, chemoresistance and epithelial-mesenchymal transition…
Abstract Over the last few years, much attention has been paid to phytocannabinoids derived from Cannabis for their therapeutic potential.…
Abstract Human immunodeficiency virus (HIV) infection and antiretroviral therapy can independently induce HIV-associated neuropathic pain (HIV-NP). There is a dearth…
Abstract Alzheimer’s disease (AD) is a neurodegenerative disorder which accounts for 60–70% of the 50 million worldwide cases of dementia…
Abstract The endocannabinoid system (ECS) is one of the most crucial systems in the human organism, exhibiting multi-purpose regulatory character.…
Abstract The connection between the endocannabinoid system (ECS) and schizophrenia is supported by a large body of research. The ECS…
Abstract Background: Methamphetamine is a highly addictive psychostimulant with reinforcing properties. Our laboratory previously found that Δ8-tetrahydrocannabinol, an exogenous cannabinoid,…
Abstract Modulating the activity of the endocannabinoid system influences various gastrointestinal physiological and pathophysiological processes, and cannabinoid receptors as well…