Peroxisomes, PPARs, and Their Role in Macrophages
Abstract Macrophages are versatile immune cells capable of modifying their functions based on their location and the specific requirements of…
macrophage polarization
Cannabinoid receptor deficiencies drive immune response dynamics in Salmonella infection
Abstract This study investigated the roles of cannabinoid receptors 1 and 2 (CB1R and CB2R) in regulating host responses to…
The Potential Value of RPS27A in Prognosis and Immunotherapy: From Pan-Cancer Analysis to Hepatocellular Carcinoma Validation
Abstract Purpose: Elucidation of the potential value of ribosomal protein S27a (RPS27A) for prognosis and immunotherapy in pan-cancer analysis, and…
BAMBI Is a Prognostic Biomarker Associated with Macrophage Polarization, Glycolysis, and Lipid Metabolism in Hepatocellular Carcinoma
Abstract Hepatocellular carcinoma (HCC) is one of the most common types of cancer worldwide. Affected patients have poor prognoses due…
Exploring the versatile roles of the endocannabinoid system and phytocannabinoids in modulating bacterial infections
Abstract The endocannabinoid system (ECS), initially identified for its role in maintaining homeostasis, particularly in regulating brain function, has evolved…
IRX5’s influence on macrophage polarization and outcome in papillary thyroid cancer
Abstract Background: With a rise in recent years, thyroid cancer (TC) is the most prevalent hormonal cancer worldwide. It is…
Cannabinoid WIN55,212-2 reprograms monocytes and macrophages to inhibit LPS-induced inflammation
Abstract Introduction: Chronic or uncontrolled activation of myeloid cells including monocytes, macrophages and dendritic cells (DCs) is a hallmark of…