lymph node metastasis

July 30, 2025

Integrin factor (FAM27E3), as a metastatic marker of papillary thyroid carcinoma, through the p53 signaling pathway promoting lymph node metastasis

Abstract Background: Papillary thyroid carcinoma (PTC) has a lymph node metastasis rate of 20%–90%. This study aims to explore the…

March 15, 2025

Identification of Novel Gene Signature Predicting Lymph Node Metastasis in Papillary Thyroid Cancer via Bioinformatics Analysis and in vitro Validation

Abstract Background: Although with a good prognosis of papillary thyroid cancer (PTC), patients with PTC and also experiencing lymph node…

June 21, 2024

An age-and sex-matched postoperative therapy should be required in thyroid papillary carcinoma

Abstract Background and purpose: Thyroid papillary carcinoma (PTC) had a high possibility of recurrence after surgery, and thyroid stimulating hormone…

April 20, 2023

Landscape of gene mutation in Chinese thyroid cancer patients: Construction and validation of lymph node metastasis prediction model based on clinical features and gene mutation marker

Abstract Objectives: Reporting the clinicopathological information of thyroid cancer (TC) patients from a central medical center of east China, and…

August 29, 2022

Comprehensive analysis of tissue proteomics in patients with papillary thyroid microcarcinoma uncovers the underlying mechanism of lymph node metastasis and its significant sex disparities

Abstract Background: Lymph node metastasis (LNM) in papillary thyroid microcarcinoma (PTMC) is associated with an increased risk of recurrence and…

June 27, 2021

A Reductionist Approach Using Primary and Metastatic Cell–Derived Extracellular Vesicles Reveals Hub Proteins Associated with Oral Cancer Prognosis

Abstract Oral squamous cell carcinoma (OSCC) has high mortality rates that are largely associated with lymph node metastasis. However, the…

February 1, 2019

Regulatory effects of hemp seed/evening primrose oil supplement in comparison with rapamycin on the expression of the mammalian target of rapamycin-complex 2 and interleukin-10 genes in experimental autoimmune encephalomyelitis

Abstract The mammalian target of rapamycin (mTOR) signaling plays a critical role in lipid synthesis and immune responses. The T…