FHL2 facilitates LUSC growth and therapy resistance through PI3K/AKT/mTOR activation
Abstract Four and a half LIM domain protein 2 (FHL2) plays a key role in tumorigenesis and progression. This study…
Abstract Four and a half LIM domain protein 2 (FHL2) plays a key role in tumorigenesis and progression. This study…
Abstract Background: SEPT9 is a pivotal cytoskeletal GTPase that regulates diverse biological processes encompassing mitosis and cytokinesis. While previous studies…
Abstract Background: Embryonic stem cell-related gene (ESRG; also known as HESRG) is a long non-coding RNA (lncRNA). It is involved…
Abstract Background: Lung squamous cell carcinoma (LUSC) ranks among the carcinomas with the highest incidence and dismal survival rates, suffering…
Abstract Endothelial cells (ECs) play an important role in tumor progression. Currently, the main target of anti-angiogenic therapy is the…
Keywords: scRNA-seq, Single-cell RNA-sequencing, CAFs, Cancer-associated fibroblasts, HGSOC, High-grade serous ovarian carcinoma, TCGA, The Cancer Genomics Atlas, LUAD, Lung adenocarcinoma,…
Keywords: LAML, Acute Myeloid Leukemia, BLCA, Bladder Urothelial Carcinoma, BRCA, Breast invasive carcinoma, CESC, Cervical squamous cell carcinoma and endocervical…
Keywords: COVID-19, coronavirus disease 2019, SARS-CoV-2, severe acute respiratory syndrome coronavirus 2, ACE2, angiotensin-converting enzyme 2, AXL, anexelekto, UMAP, uniform…
Keywords: TME, tumor microenvironment, CAF, cancer-associated fibroblasts, EMT, epithelial-mesenchymal transition, DLBC, diffuse large B-cell lymphoma, TCGA, The Cancer Genome Atlas,…
Keywords: AUC, area under the curve, CCLE, cancer cell line encyclopedia, HR, hazard ratio, ROC, receiver operating characteristic, SHCBP1, Shc…