Abstract Background: Protein S-palmitoylation is a reversible post-translational modification that plays a significant role in tumor progression. However, the impact…
Abstract Backgrounds: PANoptosis is a new form of inflammatory programmed cell death, that emphasizes the interaction between pyroptosis, apoptosis and…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-13598-9. Article type: Research Article Keywords: MCM6, Pan-cancer, Prognosis,…
Abstract Background: Cancer immunotherapy has revolutionized treatment, yet predicting patient responses remains challenging. The potential of nuclear receptor coactivator 4…
Abstract Introduction: Emerging research emphasizes the critical role of local microbiota in shaping the tumor microenvironment (TME) and influencing cancer…
Abstract Background: The membrane-spanning 4-domains subfamily A member 2 (MS4A2), a mast cell-specific IgE receptor component, exhibits paradoxical roles in…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-03946-0. Article type: Research Article Keywords: ASCC1/2/3, ASC-1 complex,…
Abstract Introduction: Lung adenocarcinoma (LUAD) has become one of the leading causes of cancer-related deaths globally, with metastasis representing the…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-024-77500-9. Article type: Research Article Keywords: NOP58 ribonucleoprotein, Lung…
Abstract Background: Neuronal guanine nucleotide exchange factor (NGEF) plays a key role in several cancers; however, its role in lung…