Variation in the co-expression profile highlights a loss of miRNA-mRNA regulation in multiple cancer types
Abstract Recent research provides insight into the ability of miRNA to regulate various pathways in several cancer types. Despite their…
Long non-coding RNA (lncRNA)
NcRNA-Mediated High Expression of HMMR as a Prognostic Biomarker Correlated With Cell Proliferation and Cell Migration in Lung Adenocarcinoma
Abstract Background: Hyaluronan-mediated motility receptor (HMMR) plays a pivotal role in cell proliferation in various cancers, including lung cancer. However,…
LIMK2 Is a Novel Prognostic Biomarker and Correlates With Tumor Immune Cell Infiltration in Lung Squamous Cell Carcinoma
Abstract Previous research found that LIM domain kinase 2 (LIMK2) expression correlated with a poor prognosis in many cancers. However,…
A Pan-Cancer Landscape of HOX-Related lncRNAs and Their Association With Prognosis and Tumor Microenvironment
Abstract The highly conserved homology cassette family (HOX) as well as 18 referenced long non-coding antisense transcripts (HOXATs) play vital…
Protein profiling reveals potential isomiR-associated cross-talks among RNAs in cholangiocarcinoma
Keywords: BLCA, bladder urothelial carcinoma, BRCA, breast invasive carcinoma, CHOL, cholangiocarcinoma, COAD, colon adenocarcinoma, ESCA, esophageal carcinoma, HNSC, head and…
Cis- and Trans-Acting Expression Quantitative Trait Loci of Long Non-Coding RNA in 2,549 Cancers With Potential Clinical and Therapeutic Implications
Abstract Many cancer risk loci act as expression quantitative trait loci (eQTLs) of transcripts including non-coding RNA. Long non-coding RNAs…
Prognostic lncRNA, miRNA, and mRNA Signatures in Papillary Thyroid Carcinoma
Abstract The current focus in the treatment of papillary thyroid carcinoma (PTC) is tumor progression. The aim of this study…
Expression and function of long non-coding RNA LINC01420 in thyroid cancer
Abstract The Human Genome Project revealed that >90% of the human genome was found to transcribe non-coding RNAs, including micro…
Long non-coding RNA small nucleolar RNA host gene 7 is upregulated and promotes cell proliferation in thyroid cancer
Abstract Thyroid cancer (THCA) is one of the most common types of endocrine cancer worldwide. However, the mechanisms underlying THCA…
Upregulation of the long non-coding RNA CASC9 as a biomarker for squamous cell carcinoma
Abstract Background: Few diagnostic and prognostic biomarkers are available for head-and-neck squamous cell carcinoma (HNSCC). Long non-coding RNAs (lncRNAs) have…