Abstract Exogenous cannabinoids have long been known to promote eating. However, the underlying mechanisms have not been completely elucidated, which…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-024-82353-3. Article type: Research Article Keywords: Cannabinoid, Motor, Sensory,…
Abstract Growth-associated protein of 43 kDa (GAP43) is a key cytoskeleton-associated component of the presynaptic terminal that facilitates neuroplasticity. Downregulation…
Abstract The lack of selective pharmacological tools has limited the full unraveling of G protein-coupled receptor 18 (GPR18) functions. The…
Abstract Cannabidiol (CBD) is the second cannabinoid, in order of importance after Δ9-tetrahydrocannabinol (THC), from Cannabis sativa. Unlike THC, CBD…
Abstract Rationale: Cannabidiol (CBD) and cannabidiolic acid (CBDA) are non-psychoactive components of the cannabis plant. CBD has been well characterised…
Abstract Clinical evidence and experimental studies have shown the psychotomimetic properties induced by ketamine. Moreover, acute or chronic ketamine (KET)…
Abstract Rationale: Opioids are effective medications, but they have several key limitations including the development of tolerance, establishment of dependence,…
Abstract Background: The endocannabinoid system interacts extensively with other neurotransmitter systems and has been implicated in a variety of functions,…
Abstract Mikania scandens (L.) Willd. (Asteraceae), known as climbing hemp weed in English, is a herbaceous climbing vine grown as…