Anti-Neuroinflammatory Cannabinoid Acids as a New Therapeutic Approach for Multiple Sclerosis
Abstract Neuroinflammation is a hallmark of multiple sclerosis (MS). MS is marked by glial cell activation, autoreactive T cells, and…
Lipopolysaccharide
Cannabidiol reduces LPS-induced inflammatory response in the human placenta by reducing NF-κB translocation
Abstract Background: Cannabidiol (CBD), a non-psychoactive cannabinoid increasingly used during pregnancy, has been proposed to modulate inflammatory processes. However, its…
Mechanisms of Salmonella typhimurium Resistance to Cannabidiol
Abstract The emergence of multi-drug resistance (MDR) poses a huge risk to public health globally. Yet these recalcitrant pathogens continue…
Complete genome sequences of eight Pasteurella multocida isolates representing all lipopolysaccharide outer core loci
Abstract Pasteurella multocida (PM) is a major bacterial pathogen that causes fowl cholera disease in both domestic poultry and wild…
Characteristics of Polysaccharides from Industrial Hemp (Cannabis sativa L.) Kernels
Abstract Polysaccharides from hemp seeds exhibit antioxidant activities in vitro and in vivo. However, crude polysaccharide quality is often low…
Antidepressant-like Effects of Cannabis sativa L. Extract in an Lipopolysaccharide Model: Modulation of Mast Cell Activation in Deep Cervical Lymph Nodes and Dura Mater
Abstract Background: Lipopolysaccharide (LPS)-induced neuroinflammation is a well-established model for studying depression-like behavior, driven by pro-inflammatory cytokines such as TNF-α…
In Vitro and In Vivo Anti-Inflammatory and Antidepressant-like Effects of Cannabis sativa L. Extracts
Abstract Cannabis sativa L. has been widely used by humans for centuries for various purposes, such as industrial, ceremonial, medicinal,…
An Emerging Strategy for Neuroinflammation Treatment: Combined Cannabidiol and Angiotensin Receptor Blockers Treatments Effectively Inhibit Glial Nitric Oxide Release
Abstract Cannabidiol (CBD), the major non-psychoactive phytocannabinoid found in cannabis, has anti-neuroinflammatory properties. Despite the increasing use of CBD, little…
Immunomodulation by cannabidiol in bovine primary ruminal epithelial cells
Abstract Background: Ruminant livestock experience a number of challenges, including high concentrate diets, weaning and transport, which can increase their…
The Anti-Inflammatory Effects of Cannabis sativa Extracts on LPS-Induced Cytokines Release in Human Macrophages
Abstract Inflammation is the response of the innate immune system to any type of injury. Although acute inflammation is critical…