A pan-cancer analysis to predict the prognosis and immunological role of copper death-related gene DLAT
Abstract As the 2nd-leading cause of death, cancer poses a serious danger to human life and health. The pathogenesis and…
immunological biomarker
Systematic pan-cancer analysis identified NCOA4 as an immunological and prognostic biomarker and validated in lung adenocarcinoma
Abstract Background: Cancer immunotherapy has revolutionized treatment, yet predicting patient responses remains challenging. The potential of nuclear receptor coactivator 4…
Pan-cancer analysis of GJB5 as a novel prognostic and immunological biomarker
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-96389-6. Article type: Research Article Keywords: Gap junction protein…
A comprehensive prognostic and immunological analysis of hexokinase domain containing protein-1 (HKDC1) in pan-cancer
Abstract Background: Currently, research on the role of hexokinase domain-containing protein-1 (HKDC1) in neoplasm metabolism remains sparse. This study seeks…
Multidimensional analysis of TMEM132A in pan-cancer: unveiling its potential as a biomarker for treatment response prediction
Abstract Background: TMEM132A is a transmembrane protein that regulates gastric cancer cell malignancy and overall survival in bladder cancer patients.…
A comprehensive and systematic analysis of Dihydrolipoamide S-acetyltransferase (DLAT) as a novel prognostic biomarker in pan-cancer and glioma
Abstract Background: Dihydrolipoamide S-acetyltransferase (DLAT) is a subunit of the pyruvate dehydrogenase complex (PDC), a rate-limiting enzyme complex, that can…
Comprehensive analysis of the oncogenic and immunological role of SPON2 in human tumors
Abstract Background: Sapiens spondin-2 (SPON2) is a protein found in the extracellular matrix that plays a role in a number…
Identification of ZBTB4 as an immunological biomarker that can inhibit the proliferation and invasion of pancreatic cancer
Abstract Background: Zinc finger and BTB domain-containing protein 4 (ZBTB4) belongs to the zinc finger protein family, which has a…
Comprehensive analysis of pan-cancer reveals the potential of SLC16A1 as a prognostic and immunological biomarker
Abstract SLC16A1 plays an important role in the development of multiple cancer types. Pan-cancer analysis may have significant impacts on…
Pan-cancer analysis of trophinin-associated protein with potential implications in clinical significance, prognosis, and tumor microenvironment in human cancers
Abstract Background: Trophinin-associated protein (TROAP), a cytoplasmic protein, is essential for microtubule cytoskeleton assembly. Mounting evidence demonstrates the vital role…