Pan-cancer Analysis Identifies AIMP2 as a Potential Biomarker for Breast Cancer
Abstract Introduction: Aminoacyl tRNA synthetase complex interacting with multifunctional protein 2 (AIMP2) is a significant regulator of cell proliferation and…
Immune microenvironment
Ferroptosis-related gene HIC1 in the prediction of the prognosis and immunotherapeutic efficacy with immunological activity
Abstract Background: Hypermethylated in Cancer 1 (HIC1) was originally confirmed as a tumor suppressor and has been found to be…
Integrated pancancer analysis reveals the oncogene characteristics and prognostic value of DIP2B in breast cancer
Abstract Background: Disco-interaction protein 2 homologue B (DIP2B) plays an important role in DNA methylation. There have been many reports…
The role of lactate metabolism-related LncRNAs in the prognosis, mutation, and tumor microenvironment of papillary thyroid cancer
Abstract Background: Lactate, a byproduct of glucose metabolism, is primarily utilized for gluconeogenesis and numerous cellular and organismal life processes.…
Characterization of SHCBP1 to prognosis and immunological landscape in pan-cancer: novel insights to biomarker and therapeutic targets
Abstract Background: Previous studies have revealed the significant roles of SHC SH2 domain-binding protein 1 (SHCBP1) in occurrence and progression…
KLF4 loss in hepatocellular carcinoma: Improving prognostic prediction and correlating immune infiltrates
Abstract Introduction: Although the molecular mechanisms of Krüpple-like factor 4 (KLF4) as a tumor suppressor in HCC tumorigenesis have been…
Prognostic and immunological role of alpha-L-fucosidase 2 (FUCA2) in hepatocellular carcinoma
Abstract Background: This study investigated the prognostic and immunological significance of alpha-L-fucosidase 2 (FUCA2) in hepatocellular cancer (HCC). Methods: The…
GPR65 as a potential immune checkpoint regulates the immune microenvironment according to pan-cancer analysis
Abstract It has been reported that inhibition of GPR65 may be effective for the treatment of certain cancers. Nevertheless, the…
Comprehensive Analysis Reveals Distinct Immunological and Prognostic Characteristics of CD276/B7-H3 in Pan-Cancer
Abstract Background: CD276 (also known as B7-H3), a newly discovered immunoregulatory protein that belongs to the B7 family, is a…
Multi-omics analyses of CD276 in pan-cancer reveals its clinical prognostic value in glioblastoma and other major cancer types
Abstract Background: CD276 (also known as B7-H3) is one of the most important immune checkpoints of the CD28 and B7…