Systematic Pan-Cancer Analysis Identifies TREM2 as an Immunological and Prognostic Biomarker
Abstract Triggering receptor expressed on myeloid cells-2 (TREM2) is a transmembrane receptor of the immunoglobulin superfamily and a crucial signaling…
immune infiltration
PDIA5 is Correlated With Immune Infiltration and Predicts Poor Prognosis in Gliomas
Abstract Gliomas are the most common and lethal primary malignant tumor of the brain. Routine treatment including surgical resection, chemotherapy,…
CTHRC1 Is a Prognostic Biomarker and Correlated With Immune Infiltrates in Kidney Renal Papillary Cell Carcinoma and Kidney Renal Clear Cell Carcinoma
Abstract Kidney renal clear cell carcinoma (KIRC) and kidney renal papillary cell carcinoma (KIRP) are the most common RCC types.…
Prognostic and immunological role of Fam20C in pan-cancer
Abstract Background: The family with sequence similarity 20-member C (Fam20C) kinase plays important roles in physiopathological process and is responsible…
An integrated pan‐cancer analysis of TFAP4 aberrations and the potential clinical implications for cancer immunity
Abstract Studies have shown that transcription factor activating enhancer binding protein 4 (TFAP4) plays a vital role in multiple types…
An Integrative Pan-Cancer Analysis Revealing LCN2 as an Oncogenic Immune Protein in Tumor Microenvironment
Abstract Background: Lipocalin 2 (LCN2), an innate immune protein, plays a pivotal role in promoting sterile inflammation by regulating immune…
The Significance of Secreted Phosphoprotein 1 in Multiple Human Cancers
Abstract Malignant tumor represents a major reason for death in the world and its incidence is growing rapidly. Developing the…
Pan-Cancer Analysis of the Mitophagy-Related Protein PINK1 as a Biomarker for the Immunological and Prognostic Role
Abstract Introduction: The PINK1 gene encodes a serine/threonine protein kinase that localizes to mitochondria and has usually been considered to…
Bioinformatics analysis of the clinical value and potential mechanisms of AHNAK2 in papillary thyroid carcinoma
Abstract Background: AHNAK2 has been recently reported as a biomarker in many cancers. However, a systematic investigation of AHNAK2 in…
Pan-Cancer Analysis of Radiotherapy Benefits and Immune Infiltration in Multiple Human Cancers
Abstract Response to radiotherapy (RT) in cancers varies widely among patients. Therefore, it is very important to predict who will…