Abstract Background: This study aims to analyze the expression patterns, clinical relevance, and biological functions of SLC16A4 across multiple cancer…
Abstract Background: Major Facilitator Superfamily Domain-containing 12 (MFSD12) has emerged as a critical transmembrane protein with increasingly recognized roles in…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-19897-5. Article type: Research Article Keywords: PD-1/PD-L1, Urothelial carcinoma,…
Abstract Background: EME1, a critical DNA repair endonuclease, has emerged as a potential oncogene implicated in genome instability and cancer…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1186/s12876-025-04295-y. Article type: Research Article Keywords: TPD52, Gastric cancer,…
Abstract Background: Charged Multivesicular Body Protein 4A (CHMP4A), a member of the ESCRT-III family, plays a pivotal role in membrane…
Abstract Background: 4-aminobutyric acid aminotransferase (ABAT) is a pivotal enzyme for mitochondrial metabolism and central nervous system homeostasis, with known…
Abstract Background: Protein S-palmitoylation is a reversible post-translational modification that plays a significant role in tumor progression. However, the impact…
Abstract Background: Colorectal cancer (CRC) is a major global health challenge, creating an urgent need to find new biomarkers that…
Abstract Papillary thyroid carcinoma (PTC) is the most prevalent form of thyroid cancer, yet its cellular heterogeneity and prognostic determinants…