Abstract Background: EEPD1 is vital in homologous recombination, while its role in cancer remains unclear. Methods: We performed multiple pan-cancer…
Abstract Background: Abnormal expression of protein tyrosine kinase 6 (PTK6) has been proven to be involved in the development of…
Abstract Background: Immune checkpoint blockade (ICB) has revolutionized the treatment of various cancer types. Despite significant preclinical advancements in understanding…
Abstract Background: Apolipoprotein E (APOE) is a polymorphic protein that plays a role in lipoprotein transformation and metabolism. It is…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1186/s12885-024-12039-6. Article type: Research Article Keywords: Pan-cancer analysis, Prognosis,…
Abstract Minichromosome Maintenance Complex Component 4 (MCM4) is a vital component of the mini-chromosome maintenance complex family, crucial for initiating…
Abstract Background: The TLC Domain Containing 1 (TLCD1) protein, a key regulator of phosphatidylethanolamine (PE) composition, is distributed across several…
Abstract Background & Aims: Small nuclear ribonucleoprotein U1 subunit 70 (SNRNP70) as one of the components of the U1 small…
Abstract Purpose: The Adhesion G protein receptor E5 (ADGRE5) gene is involved in a wide range of biological functions in…
Abstract Pyruvate dehydrogenase kinases (PDKs) play a key role in glucose metabolism by exerting negative regulation over pyruvate dehyrogenase complex…