Abstract Despite significant successes, immunotherapy continues to face numerous challenges in practical applications. CD82 plays an important role in the…
Abstract Background: The phospholipid-modifying enzyme MBOAT2 plays a crucial role in iron homeostasis by inhibiting iron sequestration, thus preventing iron-induced…
Abstract Cannabinoids relieve pain, nausea, anorexia and anxiety, and improve quality of life in several cancer patients. The immunotherapy with…
Abstract Topoisomerases are critical nuclear enzymes that resolve DNA topological challenges during genetic processes. However, there is currently a lack…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1186/s12885-024-12039-6. Article type: Research Article Keywords: Pan-cancer analysis, Prognosis,…
Abstract Introduction: The nuclear factor kB (NF-κB) pathway emerges as a critical regulator of immune responses and is often dysregulated…
Abstract It has been reported that inhibition of GPR65 may be effective for the treatment of certain cancers. Nevertheless, the…
Abstract Background: CD276 (also known as B7-H3) is one of the most important immune checkpoints of the CD28 and B7…
Abstract Clusterin (CLU) is a chaperone-like protein that has been demonstrated to have a direct relationship with cancer occurrence, progression,…
Abstract Background: DEP domain containing 1 (DEPDC1) gene is upregulated in several malignancies and contributes to tumorigenesis. Although the role…