Abstract Object: This study aimed to elucidate the role of parthanatos-related genes (PRGs) in papillary thyroid carcinoma (PTC) and construct…
Abstract Background: Skin cutaneous melanoma (SKCM) is a highly aggressive malignancy that arises from melanocytes and has been associated with…
Abstract CD93 is a highly glycosylated transmembrane glycoprotein with key functional domains, including a C-type lectin-like domain (CTLD) and epidermal…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s00262-025-04026-y. Article type: Research Article Keywords: Interferon-stimulated gene ISG15,…
Abstract Background: The widespread use of immune checkpoint inhibitors (anti-CTLA4 or PD-1) has opened a new chapter in tumor immunotherapy…
Abstract Background: Cannabis (CAN) use has risen significantly over the last few decades. CAN has potent immunosuppressive properties, which could…
Abstract Background: High levels of LLT1 expression have been found in several cancers, where it interacts with CD161 on NK…
Abstract Triple-negative breast cancer (TNBC) accounts for about 10-20% of all breast cancer cases and is associated with an unfavorable…
Abstract The immune environment in tumors is the key factor affecting the survival and immunotherapeutic response of patients. This research…
Abstract During solid tumor progression, the tumor microenvironment (TME) evolves into a highly immunosuppressive milieu. Key players in the immunosuppressive…