SLITRK2 as a prognostic and immunological biomarker in gastric cancer
Abstract Background: SLIT and NTRK-like protein 2 (SLITRK2) encodes a transmembrane protein that regulates neurite outgrowth. Some studies have demonstrated…
Immune cell infiltration
A pan-cancer analysis of the oncogenic function of HMGB1 in human tumors
Abstract Background: Although high mobility group box protein 1 (HMGB1) has been researched in relation to cancer in many investigations,…
Interplay of RNA m6A Modification-Related Geneset in Pan-Cancer
Abstract Background: N6-methyladenosine (m6A), is the most common modification found in mRNA and lncRNA in higher organisms and plays an…
UBR1 is a prognostic biomarker and therapeutic target associated with immune cell infiltration in gastric cancer
Abstract Background: Ubiquitination is a targeted protein modification process mediated by intracellular molecules. UBR1 encodes a protein that binds to…
Pan-Cancer Analysis Confirms the Prognostic and Immunological Implications of the 1,25-Dihydroxy Vitamin D3 Receptor in Cervical Squamous Cell Carcinoma
Abstract Vitamin D receptor (VDR), specifically the 1,25-dihydroxy form, holds significant importance in various types of cancer, including cervical squamous…
Role of SYT11 in human pan-cancer using comprehensive approaches
Abstract Background: Synaptotagmin 11 (SYT11) plays a pivotal role in neuronal vesicular trafficking and exocytosis. However, no independent prognostic studies…
Identification of disulfidptosis-associated genes and characterization of immune cell infiltration in thyroid carcinoma
Abstract Objective: The primary objective of this study is to conduct a comprehensive screening and analysis of differentially expressed genes…
Comprehensive pan‑cancer analysis of MTDH for human tumor prognosis and as an immunological biomarker including breast and kidney cancer
Abstract Metadherin (MTDH), initially discovered in primary astrocytes of the human fetus through rapid subtraction hybridization and labeled as astrocyte…
Increased FGF2 expression promotes immune cell infiltration and correlates with an unfavorable prognosis in thyroid cancer
Abstract To delve into the expression and functions of FGF2 in patient with thyroid cancer (THCA), we conducted a systematic…
Integrative analysis revealed a correlation of PIAS family genes expression with prognosis, immunomodulation and chemotherapy
Abstract Background: Protein inhibitor of activated STATs (PIAS) has pleiotropic biological effects, such as protein post-translational modification, transcriptional coregulation and…