A helping HAND: therapeutic potential of MAGL inhibition against HIV-1-associated neuroinflammation
Abstract Background: Human immunodeficiency virus (HIV) affects nearly 40 million people globally, with roughly 80% of all people living with…
HIV-1
Polarization of HIV-1- and CMV-Specific IL-17-Producing T Cells among People with HIV under Antiretroviral Therapy with Cannabis and/or Cocaine Usage
Abstract Objective: This study evaluated the influence of cannabis and/or cocaine use in human immunodeficiency virus (HIV)- and cytomegalovirus (CMV)-specific…
The Use of CBD and Its Synthetic Analog HU308 in HIV-1-Infected Myeloid Cells
Abstract Currently, there is no cure for human immunodeficiency virus type 1 (HIV-1) infection. However, combined antiretroviral therapy (cART) aids…
The impact of cannabinoids on inflammasome signaling in HIV-1 infection
Abstract Human immunodeficiency virus type 1 (HIV-1) is a chronic disease that afflicts over 38 million people worldwide without a…
Pharmacological, behavioural and mechanistic analysis of HIV-1 gp120 induced painful neuropathy
Abstract A painful neuropathy is frequently observed in people living with human immunodeficiency virus type 1 (HIV-1). The HIV coat…